Experimental mRNA therapy protects the liver after acetaminophen overdose

When a patient arrives at the hospital with an acetaminophen overdose, it’s often a race against the clock. The only FDA-approved antidote for overdose-related liver injury, N‑acetylcysteine, must be administered within hours to be effective.But in a new study published today in PNAS, researchers used a novel approach in an animal model that could eventually help buy more time for these patients.