Steve Gleason Ended Peyton Manning’s Entire Career With Brutal Joke On The ManningCast [VIDEO]

October 6, 2026, 9:38am EST 646 • By Darrelle Lincoln

Steve Gleason roasted Peyton Manning’s life away.

Click for sound 0:00 / 0:00 The New Orleans Saints legend appeared as a guest on the ManningCast as he joined Peyton and Eli Manning during the third quarter of the game. The broadcast featured a matchup between the Saints and the Atlanta Falcons during the 20th anniversary of his famous blocked punt from 2006.

That historic play became an iconic symbol of resilience for New Orleans. Unfortunately, the night would not go well for the team on the field. However, Steve Gleason certainly left a lasting impression.

Steve Gleason delivered a legendary burn to Peyton Manning on the Monday night ManningCast. During the live broadcast, the hosts showed an old clip of Peyton attempting a punt. Eli Manning eagerly asked the famous Saints special teams hero how easy blocking that kick would be. Gleason quickly fired back with a savage joke regarding the enormous size of Peyton’s forehead.

Using his communication device, Gleason responded: “Peyton, unfortunately for both of us, long before I hit the ball, I [‘d] hit your forehead.” This precise roast instantly triggered massive laughter from both of the amused Manning brothers. Consequently, the legendary quarterback took the comedic hit in stride.

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Gleason retired from the NFL in 2008 following an eight-season professional football career. Three years later, the former New Orleans Saints safety faced a life-altering medical diagnosis. Doctors revealed that he had amyotrophic lateral sclerosis, which is commonly known as ALS. This neurodegenerative disease completely stripped away his motor functions and his physical independence over time.

Today, Steve Gleason has survived with the progressive condition for fifteen years. He relies entirely on a mechanical ventilator to breathe. Furthermore, he has no movement in his arms or legs. The former athlete utilizes a wheelchair for mobility. He communicates letter by letter using an eye-tracking computer tablet. Despite these immense challenges, Gleason lives a purposeful life.