Premier League campaigners Medeama Sporting Club thrashed Real Tamale United 3-0 at the Tarkwa Park on Sunday to advance in the MTN FA Cup.
First half goals from Kabiru Imoro and a double from James Boadu compounded the troubles of RTU who are also battling relegation in the league.
Elsewhere, Asante Kotoko also thumped lower division side Danbort FC 3-0 at the Baba Yara Stadium.
Ivorian Ahmed Toure opened the scoring with a header under one minute inside the six-yard box by connecting Michael Akuffo’s free-kick.
Striker Nathaniel Asamoah on 37 minutes by turning inside the box to finish cooly thanks to Frank Boateng’s pass from the right.
Two minutes later, midfielder Michael Akuffo converted a penalty kick after defender Vincent Agbeyenga handled the ball inside the box.