The current shortages and price hikes have not been seen since the 2008 economic and financial crisis spiralled into hyperinflation.
Prices for many staples have more than doubled in less than a month.
The deepening economic crisis comes less than three months after Mnangagwa took over from veteran autocrat Robert Mugabe following a brief military takeover last year. He went on to win disputed elections in July.
“The situation in the hospitals is so shocking,” Chamisa said. “Our hospitals are sick. Sick hospitals can’t attend to sick people. Our people are dying from preventable diseases such as cholera.”
At least 50 people have died of cholera since September.
“There is an absence of leadership. The nation is orphaned, the nation is parentless,” Chamisa said.
A commission of inquiry is currently investigating the death of six people in post-election violence after soldiers opened fire on protesters who accused officials of delaying poll results.