Asante Kotoko ensured their bid to win the double this season remained intact after overcoming second-tier side Istanbul 3-2 in the MTN FA Cup.
The Porcupine Warriors, who are closing in on the Premier League title progress to the fifth round following their win at the Baba Yara Stadium on Sunday.
Aminu Mohammed,Larbi Koomson and Abdul Aziz Yusif got the goals for Kotoko before Felix Addo and Eric Agyei scored for Istanbul.
Kotoko, two-time losing finalist in the last three seasons of the FA Cup are aiming for a domestic double this season.
In another fixture, Feyenoord continued their unbeaten run this season in all competitions after defeating former Cup winners, New Edubiase 5-4 on penalties drawing goalless in regulation time.
The second-tier side, who have qualified for the Premier League play-offs thus progress to the quarter-final stage of the competition.