A notable inclusion is Athletic Bilbao right-back Andoni Iraola, with The 28-year-old looking to add to his four caps for Spain.
Javi Martinez and Juan Mata, who played a part in the summer World Cup win, are reintroduced after a spell in the under-21 squad.
Del Bosque has had to contend with injuries to key players, with Cesc Fabregas, Carles Puyol and Pedro all missing out through injury.
The squad list in full:
Goalkeepers: Iker Casillas, Pepe Reina, Victor Valdes
Defenders: Raul Albiol, Alvaro Arbeloa, Joan Capdevila, Carlos Marchena, Andoni Iraola, Gerard Pique, Sergio Ramos
Midfielders: Xabi Alonso, Sergio Busquets, Xavi, Andres Iniesta, Santi Cazorla, Javi Martinez
Forwards: David Villa, Fernando Llorente, Fernando Torres, David Silva, Juan Mata, Jesus Navas
The rest is here:
Juan Mata And Javi Martinez Return To Spain Squad For Euro 2012 Qualifiers